CASE REPORT
A Rare Case of Methicillin-Resistant Staphylococcus aureus Pyomyositis in a Patient with Chronic Granulomatous Disease
Sunit Sikdar, Megha Priyadarshi, Kartik Aggarwal, Amandeep Singh, Surabhi Vyas, Upendra Baitha*
JASPI December 2025 / Volume 3 /Issue 4
Copyright: © Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Sikdar S, Priyadarshi M, Aggarwal K, et al.A Rare Case of Methicillin-Resistant Staphylococcus aureus Pyomyositis in a Patient with Chronic Granulomatous Disease.JASPI. 2025;3(4)26-30
DOI: 10.62541/jaspi100
ABSTRACT
A 40-year-old male with uncontrolled diabetes presented with anterior chest wall and right thigh swelling. CT imaging revealed a superficial abscess in the chest wall and a multiloculated pus collection in the subcutaneous and intermuscular planes of the right gluteus and quadriceps, consistent with pyomyositis. Pus cultures grew MRSA. Immunological workup identified chronic granulomatous disease, indicating defective NADPH oxidase function in leukocytes. The patient was treated with targeted antibiotics and surgical incision and drainage. Following six weeks of antibiotic therapy, he was discharged in stable condition with appropriate prophylaxis to prevent recurrence.
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Copyright © Author(s) 2025. JASPI- Journal of Antimicrobial Stewardship Practices and Infectious Diseases.